The article is based on a qualitative study using narrative interviews with 13 South Bohemian Pervitin users who visit the drug advisory centre. The goal of the article is to describe how social exclusion is subjectively experienced by Pervitin users. The data were processed with the help of grounded theory. The respondents feel to be excluded in a number of normal life areas: they are rejected by their family, friends, and also by public institutions - particularly by the police and by health care facilities. Social exclusion is accompanied by feelings of guilt and remorse for the users. They are also ashamed of their situation, feeling sorrow and disappointed themselves. In some cases, the users are angry with themselves, in other cases with their surroundings for rejecting them. In both variants, exclusion may constitute an important factor in reducing the users' chances of abstinence.