Statistics situates infertility as a global health issue with about 48 million couples and 186 million individuals. The rate at which IVF and surrogacy arrangement have been engaged globally has raised alarm to scholars in medicine, sociology, law, social work, psychology, and religion among other fields. Improved methods and unarguable advantages of surrogacy particularly to couples in dire need of children has left even more questions unanswered. The focus of this research is placed on the interdisciplinary factors that influences the practice of surrogacy. Due to the paucity of data on the subject, a systematic review of relevant published articles dated until 2023 were engaged within survey design. This study argues that surrogacy is not welcomed in many societies, however, it is also clearly noted that it is currently practiced in several countries. Interdisciplinary collaboration has been situated within surrogacy practice, and the findings of this study is prominent for such.