Weather conditions are extremely influential on grapevine productivity and quality. High temperature and humidity makes favorable conditions for powdery mildew infection respectively. The meteorological data around Keszthely, Hungary show the vegetative period is dryer and warmer than it was closely hundred years ago. We examined the developmen...t of powdery mildew infection on two variet ies Vitisvinifera L. cv Italian Riesling and cv Merlot in relation with meteorological data. No primer infections were appeared in the vineyard. The year of 2008 was quite ideal for the accumulation of Erysiphe necator in the experimental vineyard. Although the dry summer can lower the infection, but if the high temperature is coupling with rainfall, the possibilities of powdery mildew infection is going to grow higher during the upcoming years.