In Hungary, raising the standards of public health and immunization against certain infectious diseases began in the 1930s. The Royal Hungarian National Public Health Institute and the related institutional system played an outstanding role in this process. The primary mission was to diagnose and research communicable diseases. Therefore, a public health, a disinfection and infectious supplier, a malaria station and a vaccine production institute were established in Ungvár. The tasks included research, healing, counselling, defence and experimental work. Researchers at the institutes developed vaccines and new methods of diagnosis that were introduced later. As a result, the proportion of infectious diseases in the country decreased.