This paper reports new floristic data of 161 taxa. Most of these data were collected between 2011–2013, and are coming from the northern edge of the floristic region 'Crisicum', the NE part of the Great Hungarian Plain, which is a little-known area from a floristic point of view. 43 CEU quarterquadrates and territory of 35 settlements are represented by the dataset. The paper reports occurrence localities for legally protected (e.g. Ophioglossum vulgatum, Stellaria palustris, Ranunculus polyphyllus, Thlaspi jankae, Lathyrus palustris, Elatine spp., Lycopsis arvensis, Lindernia procumbens, Cirsium brachycephalum, Cyperus pannonicus), strictly protected (Armoracia macrocarpa, Vicia biennis) and some little-known (e.g. Cardamine parviflora, Reseda luteola, Melilorus dentatus, Veronica catenata) taxa. Numerous data of alien species (e.g. Lepidium densiflorum, Euphorbia maculata, Sicyos angulatus, Erechtites hieracifolia, Elodea nuttallii, Elymus elongatus, Eleusine indica, Sorghum halepense, Eriochloa villosa) are also published. The most important data are documented by voucher specimens deposited in herbarium of Debrecen University (DE).