The paper presents research results obtained in stationary experiments, carried out at Agricultural Research and Development Station Oradea, regarding the influence of nitrogen, phosphorus and potassium fertilizers, on Cd, Pb, Cu, Zn and Ni concentration on wheat grains.

The minimum concentration of cadmium in wheat grains was recorded in the case of the unfertilized plot N0P0K0, 0.12 mg kg^-1, and maximum value 0.22 mg kg^-1, was registered at the fertilized plot with N160P80K120, relative difference relative to control was 84.2%.

Lead concentration had the lowest value in the unfertilized plot, the value (0.4 mg kg^-1) being under the maximum allowed (1.0 mg kg^-1). In case of the fertilized plot with N160P80K120, the lead concentration had the highest value, 0.47 mg kg^-1, but even in this case it was located beneath the maximum limit allowed.

In all four systems of fertilization, copper has not exceeded the maximum allowed limit (5 mg kg^-1), the values have been comprised between 1.68 mg kg^-1 at the unfertilized plot and 2.81 mg kg^-1 at the fertilized plot with N160P80K120. In other plots of fertilization copper had concentrations of 1.97 mg kg^-1, at the fertilized plot with N80P40K40, and 2.78 at the fertilized plot with N80P80K80.

The lowest concentration of zinc, 26.47 mg kg^-1, has been registered in the control N0P0K0. In the other fertilization plots studied, the zinc concentrations had the following values: 27.66 mg kg^-1 (N80P40K40), (N80P80K80) 29.87 mg kg^-1 and 33.62 mg kg^-1 (N160P80K120).

Nickel has registered the lowest value in the unfertilized plot, 3.47 mg kg^-1. The fertilized plot with N160P80K120 had the highest value 4.94 mg kg^-1, with 42.39% higher compared to the control N0P0K0.