Due to advancing technology; nowadays mobile robot applications in hospitals have been increased. For that reason, it is very important and necessary to analyze the trajectory of such helping robotic system. However; there are many types of mobile robots have been utilized in hospital applications such as helping nurses. In this simulation study; a designed and controlled mobile robot was controlled by using standard feedback controllers. On the other hand, the robot was also tested with disturbances of ground surface roughness. The simulation results were improved that standard PID controller has superior performance to overcome surface roughness of the robot trajectory.