Different Cropping Systems have many advantages and ensure better crop growth and yielding. Its combination with other agronomic measures can ensure optimal crop density for maximum crop growth and photosynthesis efficiency. The aim of this study was to investigate the influence of different cropping systems on monoculture and biculture rotations [maize- wheat]. The study found that crop rotation does not have a significant effect on the grain nutrition quality, Leaf Area Index (LAI) and Normalized Difference Vegetative Index (NDVI) but has a significant effect on the Soil-Plant Analysis Development (SPAD). Yield and yield components were significantly influenced by crop rotation in this study as yield, plant height, cob weight and number of grains per row all recorded lower mean at 5% probability levels.